Preoperative significance of thyroglobulin, thyroid stimulating hormone and thyroglobulin antibody in differentiated papillary thyroid carcinoma
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چکیده
منابع مشابه
Thyroid-stimulating hormone, thyroglobulin, and thyroid hormones and risk of differentiated thyroid carcinoma: the EPIC study.
BACKGROUND Increased levels of thyroglobulin (Tg) and thyroid-stimulating hormone (TSH) are associated with differentiated thyroid carcinoma (TC) risk, but strong epidemiological evidence is lacking. METHODS Three hundred fifty-seven incident TC case patients (n = 300 women and 57 men; mean age at blood collection = 51.5 years) were identified in the EPIC cohort study and matched with 2 (wome...
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~-14C]Tyrosine-labeled noniodinated hog thyroglobulin was iodinated enzymatically and nonenzymatically (iodine, iodide-chloramine-T, pH 7.4, or iodine monochloride, p.H 8.1). This led to similar levels of iodine incorporatzon as well as of thyroid hormone synthesis. Iodine monochloride at pH 5.5 formed “hormonogenic” iodotyrosine residues, but no hormone residues. The latter were formed when th...
متن کاملThyroglobulin value in patients surgically treated for differentiated thyroid carcinoma
Gostimir MIKAČ Faculty of Medicine Save Mrkalja 22 78000 Banja Luka Republic of Srpska Bosnia and Herzegovina [email protected] SUMMARY Introduction Thyroglobulin is composed glycoprotein, and it is synthesized by follicular cells of the thyroid gland. Treatment of differentiated thyroid carcinomas involves total thyroidectomy followed by radioiodine ablation of a potential remaining tissue. The m...
متن کاملSerum thyroglobulin autoantibodies: prevalence, influence on serum thyroglobulin measurement, and prognostic significance in patients with differentiated thyroid carcinoma.
The prevalence of circulating thyroid autoantibodies (TgAb or antithyroid peroxidase) was increased nearly 3-fold in patients with differentiated thyroid cancers (DTC) compared with the general population (40% vs. 14%, respectively). Serum TgAb (with or without antithyroid peroxidase) was present in 25% of DTC patients and 10% of the general population. Serial postsurgical serum TgAb and serum ...
متن کاملMelatonin in the thyroid gland: regulation by thyroid-stimulating hormone and role in thyroglobulin gene expression.
Melatonin is an indoleamine with multiple functions in both plant and animal species. In addition to data in literature describing many other important roles for melatonin, such as antioxidant, circadian rhythm controlling, anti-aging, antiproliferative or immunomodulatory activities, our group recently reported that thyroid C-cells synthesize melatonin and suggested a paracrine role for this m...
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ژورنال
عنوان ژورنال: International Surgery Journal
سال: 2019
ISSN: 2349-2902,2349-3305
DOI: 10.18203/2349-2902.isj20195379